Houston We Have a Podcast
Episode•March 6, 2026•49 min

Science in Space

Dr. Lisa Carnell, division director for NASA’s Biological and Physical Sciences, breaks down how research in microgravity, the Moon, and Mars can transform what we know about biology and physics. HWHAP 414.

Key Takeaways

  • 1

    The critical role of fundamental research in space

    Fundamental research acts as the building block for all applied sciences and future technologies.

    Microgravity provides a unique environment to study phenomena like fluid dynamics, combustion, and quantum mechanics that are impossible to replicate on Earth.

  • 2

    Advancing human health through space-based innovation

    NASA is using 'organ-on-a-chip' technology to study how individual astronauts respond to deep space radiation.

    Research into bone loss and immune system changes in space helps develop personalized medical countermeasures for future missions to the Moon and Mars.

  • 3

    The importance of a 'space labs' approach

    NASA is shifting toward a model where science is conducted on any available platform, including the Moon, deep space, and commercial LEO destinations.

    Integrating crew members into real-time experimental iteration significantly accelerates the pace of scientific discovery.

  • 4

    Building a sustainable orbital economy

    NASA is actively fostering a commercial low-Earth orbit economy by partnering with private entities to utilize space stations for research.

    This commercialization ensures that space remains accessible for diverse research needs while maintaining American leadership in space exploration.

Intro

  • Dr. Lisa Carnell, Division Director for NASA’s Biological and Physical Sciences, joins the podcast to discuss how research in microgravity and deep space environments is transforming our understanding of biology and physics.
  • Dr. Lisa Carnell is the Division Director for NASA’s Biological and Physical Sciences. With a Ph.D. from Duke University and eight patents, she has a background in technology transfer, space radiation medical countermeasures, and translational research.

– From Iowa Cornfields to Engineering

  • Dr. Carnell shares her journey from growing up in a small town in Iowa to becoming an engineer, driven by a fascination with how things work.

I was really fascinated with inventions. And I thought, I want to be an inventor somehow.

– Dr. Lisa Carnell

– Bridging Engineering and Biology

  • Dr. Carnell explains how she merged mechanical engineering with biomedical research, leading to her work with piezoelectric materials and medical implants.

– Defining Biological and Physical Sciences

  • An overview of the BPS portfolio, covering everything from microbes and plants to combustion, fluids, and quantum science.

– The Five Pillars of BPS Research

  • Precision Health
  • Space Crops
  • Quantum Leaps
  • Foundations
  • Space Labs

– Avatar and Personalized Medicine

  • Discussion on the 'Avatar' experiment, which uses organ-on-a-chip models derived from crew members to study the effects of deep space radiation.

– Advice for Future Scientists

Don't shy away from opportunities when they present yourself. If you have ideas and go create it, be proactive, you know, go after it.

– Dr. Lisa Carnell

Resources

Topics

NASAMicrogravityBiological SciencesPhysical SciencesSpace ExplorationBiomedical EngineeringQuantum PhysicsArtemis

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